Using a stand mixer fitted with the whisk attachment, or in a large mixing bowl using a hand-held mixer, mix the cream cheese until smooth.
Mix in the powdered sugar and vanilla extract until well combined, scraping down the sides of the bowl as needed.
Add in the heavy whipping cream and continue mixing on medium speed until the mixture has thickened and soft peaks form. Set aside.
Start by layering half of the angel food cake in a large trifle dish, then layer half of the cheesecake filling on top, then top with the blueberries (you can reserve some for the top if you prefer).
Layer the other half of the angel food cake on top of the blueberries followed by the other half of the cheesecake filling, then top with the sliced strawberries and reserved blueberries.
Cover tightly and refrigerate until ready to serve.